grain-elipse1
grain-elipse

Epigenetics and all you need to know about it

Published August 16, 2022
Categories: Health Science
Epigenetics

Every cell in our bodies encloses the same genetic data, a complete and exceptional blueprint that creates the person. What makes a brain cell differ from a heart cell, or any other cell is the activation and inactivation of certain genes. The study of learning the aspects that regulate the activity of genes is called epigenetics.

What is epigenetics?

Generally, most people understand what genetics is: this study`s subject is genome, its modifications, and the peculiarities of the transmission of specific features from one generation to another. Epigenetics is a branch of biology that studies such modifications in the genes’ activities, in which the structure of DNA stays the same.

The word “epigenetics” was first introduced in 1942 by Conrad Waddington, an English scientist. The scientist explained it as something that connects genetics and epigenesis, the doctrine of sequential embryonic development. His suggestion was extraordinary at those time but completely confirmed now.

Our genes are identical when we are young, old, healthy, or sick – they don’t just pass on their genome. How does this work? When we get old or under the weather, we experience the responses of our body to epigenetic changes. It has been proven for instance, that most chronic illnesses such as heart disorders and malignant neoplasm can be linked to modifications in epigenetic indicators. Equivalently, our surroundings and lifestyle define how our genome is adjusted to positive or negative environments. A person’s behavior, diet or daily routine impact which genes will increase or, conversely, weaken their activity. And – the most essential thing about it – this information can be inherited. Epigenetic processes begin before birth and continue throughout a person’s life. Unlike genetic data, epigenetic changes can be reproduced in three or four generations, and in the absence of triggers that stimulate them, they disappear.

Study on epigenetic cell memory

If only the genes were the key aspect that determines our developing, all people would be identical. Due to the epigenome, we do have different appearances and in the same family children have a bunch of unique features:

  • are born with different hair structures and colors,
  • with different eye colors,
  • with or without being prone to weight gain or not, etc.

The impact of epigenetic factors on health was learned by Dutch and US researchers who analyzed the lives of elderly Dutch people born in the post-war period between 1945 and 1946. The malnutrition and war-related stress of their mothers have been discovered to have an adverse effect on the health of unborn children. They were born prematurely and very prone to vascular disorder, obesity, and type 2 diabetes. It is essential to mention that their children were also born prematurely, though the mothers’ nutrition was already balanced enough. This evidences that such changes can be passed on to the next generations.

What affects the human epigenome

The human epigenome is mainly impacted by lifestyle factors: the quality of diet, stress, sport, bad and good habits, etc. Nevertheless, many substances can also impact heredity. For instance, bisphenol-A, which is applied as a hardener in plastics, breaks free methyl groups and inhibits the enzymes that connect these groups with DNA. This substance contributes to getting breast, prostate, and testicular cancer, obesity, type 2 diabetes, and reproductive disorders among others. Additionally, some foods positively affect the epigenome: green tea, the majority of vegetables, and fruits. Should the person add them to his or her diet, the likelihood of getting cancer is reduced.

Interestingly, humans can find keys to gene control, and maybe we will be able to regulate such physical processes that occur in the body as aging. Genes can be under control by purposefully influencing their expression. This is the main modern approach to health betterment and life-prolonging. Due to directed gene expression, in the future, we could achieve mental superpower, renew organs and body systems, and stop aging. So far, this is only a suggestion that requires further investigation, but research is already in progress to stop the growth of cancer cells by controlling gene activities.

We are able to control epigenetic mechanisms to a certain degree through positive lifestyle changes. For instance, getting rid of the smoking habit increases DNA methylation. Taking folic acid while pregnant can reduce the risk of many birth defects in the baby. Or a balanced diet and regular sport also spur positive changes not only in your life but also further generations.

Related insights

September 29, 2022
Categories: Health Science

CRISPR-Based HIV Gene Therapy Administered To First Human Patient

Scientists at the Lewis Katz School of Medicine at Temple University and representatives of Excision BioTherapeutics together succeeded in applying...
September 28, 2022
Categories: Science

How long did our ancestors live?

Looking at the possibilities of modern medicine and the variety of healthy diets, it is easy to assume that our...
September 23, 2022
Categories: Science

Scientists are using AI to create new proteins

Tremendous developments in the field of computer science open up multiple possibilities and due to it biologists can dream up...
September 21, 2022
Categories: Health

Food safety tips for climate changing era

Climate changes, which have been taking place on our planet over the past decades at a rapid pace, is one...
September 21, 2022
Categories: Science

Universal Artificial Blood

Japanese researchers have managed to invent artificial blood, unique in its properties. The outcomes and description of study were demonstrated...
Prev
Next

Have any questions?

Send us a request and we will contact you as soon as possible.

loader

We are in social networks

  • The goal that we have set for ourselves is the acquisition by the human body of the ability to remain young and healthy as long as possible – practically, the acquisition of immortality by a person.

    A young man at 100 years of age? Why not? And this is just the tip of the iceberg of our plans.

  • The main and most global goal of the project is to gain immortality. However, to achieve this goal, there is a lot of work to be done: from introducing the latest developments in medical practice, which already now can significantly improve health and prolong life, to conducting scientific research that will help achieve our global goal.

  • A fund or a company interested in investing in our project can contact us via the contact form to clarify all the details. The main condition is the sharing of project values ​​and the desire to change the world for the better together with us.

    In addition, we plan to issue our own token, by purchasing which you will also be able to invest in the project.

  • Since we create the ELC project from scratch and fully cover all our activities in social networks, you can learn about all promotions and developments from our official pages and website. One of the first public results will be the presentation of the project at the Eternity Life Forum, where we will present our project, with its ideas and developments.